Apoptosis regulation in adrenocortical carcinoma
نویسندگان
چکیده
منابع مشابه
Cutaneous metastasis in a patient with adrenocortical carcinoma
Adrenocortical carcinoma is an uncommon and aggressivemalignancy. Despite a high frequency of metastasis, cutaneousmetastasis of adrenocortical carcinoma is rare with only isolatedcase reports. Its diagnosis can be challenging based solely onhistopathological findings. Yet, the clinical history in combinationwith an immunohistochemical panel consisting of inhibin,vimentin, chromogranin, synapto...
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Adrenocortical carcinoma (ACC) is an orphan malignancy that has attracted increasing attention during the last decade. Here we provide an update on advances in the field since our last review published in this journal in 2006. The Wnt/β-catenin pathway and IGF-2 signaling have been confirmed as frequently altered signaling pathways in ACC, but recent data suggest that they are probably not suff...
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normal adrenal biosynthetic pathway from pregnenolone to corticosterone is intact: (c) the biosynthesis of deoxycorticosterone to corticosterone from pregnenolone is at a reduced level as compared to the normal adrenal cell, indicating a reduced 1l/3-hydroxylase activity: and (d) (20S)-20-hydroxycholesterol can be converted to corticos terone, thus indicating a defect in the tumor system normal...
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Nonfunctional adrenocortical carcinoma is an extremely rare malignant tumor in children. Unlike the functional tumor which is detected early due to its hormonal presentation, nonfunctional tumor is detected at a later stage. Here we report a case of a 10 year old girl who presented with abdominal mass and symptoms of short duration. No hypertension and cushingoid features were seen. Serum alpha...
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F-18 FDG is the most widely used tracer in molecular imaging and it is applied for many purposes mainly in malignant diseases. Incidental finding are common in FDG-PET/CT imaging and includes benign and malignant lesions. Among the rare tumors , adrenal oncocytomas are uncommon findings and incidental findings of thyroid malignancies are not rare. Oncocytoma is a rare adrenocortical tumor and m...
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ژورنال
عنوان ژورنال: Endocrine Connections
سال: 2019
ISSN: 2049-3614
DOI: 10.1530/ec-19-0114